Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Control of polymerization by J chain
نویسندگان
چکیده
منابع مشابه
PREPARATION OF ENRICHED IMMUNOGLOBULIN M AND IMMUNOGLOBULIN A FROM HUMAN PLASMA
As IgM and IgA-enriched preparations are needed to complete the immunotherapeutic spectrum, a simple procedure is described for the preparation of IgM and IgA enriched immunoglobulins. Fraction III which was prepared by cold ethanol fractionation was treated by octanoic acid followed by ethanol precipitation and ion-exchange chromatography using Sephadex DEAE A-50 and 0.1 M tris-D.35M NaCI ...
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متن کاملSecondary structure of the immunoglobulin J chain.
J chain is a 137-residue polypeptide that is covalently linked to polymeric immunoglobulins and participates in their synthesis and transport to external secretions. To clarify these roles, the secondary structure of J chain was characterized by computer-assisted analyses of human and mouse sequences and by circular dichroism measurements of the isolated J chain. The secondary-structure profile...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1973
ISSN: 0306-3283
DOI: 10.1042/bj1360607